Porous materials for HPLC (High performance liquid chromatography)

Porvair manufacture sintered metal powder frits and cups used within the HPLC & UPHLC equipment.

These include column frits and solvent filters in materials such as Stainless Steel, Titanium, Hastelloy C276 and Hastelloy C22 and are available in a variety of pore sizes.

Column Support Frits 

Purpose 

• Retain packing material at both ends of the liquid chromatography column.
• Provide uniform flow of sample into column.

Features and Benefits

• Precisely fit customer’s dimensional requirements
• Withstand high-pressure applications.
• Passivation offered for corrosion resistance.
• With or without chamfer
• Inert (Titanium frits for bio columns)
• Can be supplied as a disc or press-fit into ring (often PEEK)

Solvent filters

Inlet solvent filter (sinker), inline solvent filter, pre-column filter and guard column filter

Inlet solvent filter

Purpose

• Protect HPLC pump inlet check valves from particulate.
• Function as a sinker to hold the pump inlet tubing to bottom of solvent supply.
• Removes the need for a pre-filter.

Inline solvent filter

Purpose

• Protects the sample injection valve from naturally occurring seal wear.
• Prevents downstream damage to components. 

Pre-column filter and Guard column filter

Purpose

• Traps particulate during mobile phase.
• Prevents pressure build-up within the column.
• Extended life of Column
• Guard columns have the additional benefit of using the same packing materials as the column to collect materials that would otherwise collect within the column. 

Solvent Filters Features & Benefits 

• Uniform Porosity
• Tortuous paths providing even flow.
• Precise Manufacturing
• Strict Process & Quality Control
• Non-shedding
• Consistent & Repeatable Flow Through the filter
• Depth Filtration
• Repeatable Control
• Filter Integrity
• Extended life of HPLC and UHPLC systems and components

What Porvair Can Offer

• Strong History in providing high-quality HPLC filters.
• Meet customer custom designs offering a high-quality solution.
• Onsite Citric Passivation
• Can be surface treated to improve inertness.
• Lab Testing and material development available
• Latest manufacturing technologies
• Latest Inspection technologies
• Conform to ISO9001
• ISO 4003 Æ Determination of Bubble Point Pore Size in Porous Sintered Metal